What Is the Cost of Chemotherapy for Dogs?


Andy Chang

- Updated March 1, 2024

What Is the Cost of Chemotherapy for Dogs?

Chemotherapy is a common therapeutic option in veterinary medicine, particularly for our canine companions. Like us, dogs can suffer from cancer, impacting their quality of life. Chemotherapy offers hope in these situations, providing relief from symptoms and a chance for remission or extended life.

What is Chemotherapy for Dogs?

Chemotherapy for dogs is a medical treatment involving administering drugs to combat and manage cancer. Just as in human medicine, these drugs are supposed to target and inhibit the growth of cancer cells. However, there are some key differences in chemotherapy in dogs compared to humans.

Canine chemotherapy is a systematic approach to treating cancer in dogs. It uses a range of powerful medications that veterinarians select and administer. Administration methods may include intravenous injections and oral pills.

Canine chemotherapy seeks to eliminate the cancer or achieve long-lasting remission. This curative approach is more common when veterinarians diagnose the cancer at an early stage and is a type that is responsive to chemotherapy. Sometimes, the goal of canine chemotherapy is palliative care. This approach aims to alleviate symptoms, reduce pain, and improve the dog’s quality of life. Palliative chemotherapy may not eradicate the cancer but can slow its progression.

Chemotherapy for dogs is typically less aggressive than in humans, focusing on minimizing side effects to maintain the dog’s quality of life. Veterinarians often employ lower doses of chemotherapy drugs to balance effectiveness and tolerability. Dogs also don't typically lose their fur during treatment.


Main Causes Necessitating Chemotherapy

Chemotherapy for dogs combats various types of cancer that can afflict our canine companions. These cancers can arise from multiple factors, including genetic predisposition, environmental influences, and age-related changes. Understanding the leading causes of cancer in dogs is crucial to determining when chemotherapy may be necessary.


This aggressive cancer affects the blood vessels and is most seen in middle-aged to older dogs, particularly breeds like German Shepherds, Golden Retrievers, and Boxers. Hemangiosarcomas have three forms and can affect the skin, spleen, or heart. Hemangiosarcoma of the spleen is the most common type and often presents with internal bleeding that may require emergency surgical treatment. Early detection can be challenging, and chemotherapy may slow its progression and alleviate symptoms.


Lymphoma is one of the most common cancers in dogs and can affect dogs of any age or breed. It arises in the lymphatic system, which is made up of lymphatic vessels, lymph nodes, and even the liver and spleen, and is a vital part of the immune system. Chemotherapy is often the primary treatment for lymphoma, and it can be effective, with many dogs achieving remission and a good quality of life.


This aggressive bone cancer primarily affects large dog breeds like Great Danes and Rottweilers. Osteosarcoma often necessitates the amputation of the affected limb, followed by chemotherapy to manage potential metastasis to other body parts. Pets can develop osteosarcoma in any bone, but it most commonly occurs in the leg bones.

Mast Cell Tumors

Mast cell tumors are the most common skin cancer type in dogs, and they range in severity from benign to malignant. Veterinarians often use chemotherapy along with surgery for aggressive tumors or alone in cases where surgery isn't an option due to tumor location or extent.

Mammary Cancer

Unspayed female dogs are at higher risk of developing mammary cancer, and chemotherapy may apply in advanced cases. Dogs that get spayed later in life may also be at higher risk. Spaying before the first or second heat cycle can reduce this risk. These tumors vary in severity, with about 50 percent being malignant and 50 percent benign. Surgery is the most common treatment and is often necessary for definitive diagnosis.

Bladder Cancer

This cancer, particularly transitional cell carcinoma, can affect the urinary tract in dogs. Chemotherapy may become part of a multimodal approach to manage this type of cancer.

The prevalence of these cancers varies among breeds and geographic regions. Some breeds are predisposed to specific types of cancer, while others may be due to environmental factors, such as exposure to carcinogens. Early detection and intervention are essential to improving the prognosis for dogs with cancer, and chemotherapy plays a crucial role in managing these conditions and extending a dog’s quality of life.

It’s worth noting that, while cancer is a significant concern for dogs, advances in veterinary oncology have made it possible to treat and manage many cases effectively, improving the overall outlook for our beloved pets facing these challenging diagnoses.


Symptoms Indicating the Need for Chemotherapy

Recognizing the need for chemotherapy in dogs often begins with identifying specific clinical signs suggesting cancer. While these signs can vary depending on the type and stage of cancer, some common symptoms may prompt further investigation and lead to discovering cancer. It's also important to note that many other diseases and conditions can cause these symptoms, so it's always best to get a veterinary evaluation to be sure.

Unexplained Weight Loss

Sudden weight loss is one of the early warning signs of cancer in dogs. A dog losing weight despite maintaining a regular diet and activity level can indicate an underlying health issue, including cancer.

Lethargy and Weakness

Dogs with cancer may exhibit general fatigue, weakness, and a lack of interest in their usual activities. These changes in energy level may be concerning, especially if they persist.

Changes in Appetite

A significant change in a dog’s appetite, either a sudden increase or decrease in food intake, is a red flag for an underlying problem such as cancer.

Lumps and Swelling

The presence of palpable lumps or masses on a dog’s body, particularly if they are growing or changing in appearance, may indicate tumors. Owners may notice skin tumors, for example, during routine grooming or petting.

Difficulty Breathing

Respiratory issues like coughing or difficulty breathing can point to cancer affecting the lungs or other parts of the respiratory system.

Changes in Behavior

Dogs with cancer may exhibit behavioral changes, such as increased restlessness, aggression, or withdrawal. These changes can result from pain or discomfort associated with disease.

Gastrointestinal Symptoms

Vomiting, diarrhea, or other gastrointestinal issues can occur with cancer in the digestive system. To confirm the presence of cancer and determine the need for chemotherapy, veterinarians employ various diagnostic procedures, including biopsy, imaging, blood tests, and fine needle aspirations.

Once a definitive cancer diagnosis occurs, the veterinarian can work with the dog’s owner to determine the most appropriate treatment plan, which may include chemotherapy. The choice to proceed with chemotherapy depends on factors such as the type of cancer, its stage, the dog’s overall health, and the owner’s preferences. Early detection and diagnosis are vital to improving the prognosis and the quality of life for dogs facing cancer.

Breeds Most Prone to Cancers Treated with Chemotherapy

Several breeds are predisposed to certain types of cancer commonly treated with chemotherapy. These genetics and hereditary factors make early detection and vigilant monitoring essential for these breeds. Here are some specific breeds and the cancers they are more prone to.

Golden Retrievers

Golden Retrievers are known to have a higher risk of developing cancer, particularly hemangiosarcoma, lymphoma, and mast cell tumors. Hemangiosarcoma often affects the spleen and heart, while lymphoma affects the lymphatic system. Genetic factors apparently contribute to their increased susceptibility to these cancers.


Boxers are at an elevated risk of developing several types of cancer, including lymphoma, mast cell tumors, and brain tumors. While the precise genetic factors are not fully understood, there appears to be a genetic component to these breed-specific cancer tendencies.


Rottweilers are prone to osteosarcoma, a highly aggressive bone cancer. This breed’s genetic predisposition to the disease has led to ongoing research into the underlying genetic markers that may contribute to its development.

Bernese Mountain Dogs

This breed is at a higher risk of developing histiocytic sarcoma, a rare and aggressive cancer that affects the immune system. Genetic factors are suspected to influence their susceptibility to this cancer.

Scottish Terriers

Scottish Terriers are predisposed to developing bladder cancer, specifically transitional cell carcinoma. Experts believe hereditary factors are involved in the increased risk.

Boston Terriers

Boston Terriers are more prone to developing mast cell tumors, particularly in the skin. While the exact genetic basis is not well-established, breed-specific tendencies are common knowledge.

Saint Bernards

Saint Bernards are at an elevated risk of developing bone cancer, including osteosarcoma. It’s important to note that while certain dog breeds have a higher predisposition to specific cancers, individual dogs within these breeds can vary in risk factors. Mixed-breed dogs can also develop cancer.

How Much Does Chemotherapy for Dogs Cost?

The cost of chemotherapy for dogs can vary widely depending on several factors, including the type of cancer, the stage of the disease, the treatment protocol, and the location of the veterinary clinic. On average, pet owners pay $3,000 to $7,000 or more for a full course of chemotherapy for their dogs. Note that this is a general range, and costs can exceed this estimate. For some types of cancer, modified chemo protocols may be less expensive. However, they may also be less effective but can buy some time and comfort in cases where a full chemo protocol isn't financially an option.

Here are some key factors that can affect the price of chemotherapy for dogs.

Type and Stage of Cancer

These factors can influence the cost of treatment. Some cancers require more aggressive or prolonged chemotherapy regimens, while others may respond to less intensive therapy.

Treatment Protocol

The choice of chemotherapy and frequency of administration rest on the veterinarian’s recommendations and the dog’s individual needs. More specialized or advanced treatment protocols may come with higher costs.

Diagnostic Procedures

The cost of biopsies, imaging tests, and blood work can add to the expense.

Duration of Treatment

Chemotherapy often lasts for several sessions over several months. The longer the treatment period, the greater the cost.

Medication Costs

The price of chemotherapy drugs can vary. Some medications are more expensive than others, and the chosen drugs depend on the specific cancer.

Veterinarian and Clinic Fees

Costs can vary based on the expertise and location of the veterinary clinic. Specialty oncology centers may have higher prices compared to general veterinary practices. However, general practices may not stock chemotherapy medications or feel comfortable handling chemo treatments, so oncologists are often necessary for the most advanced chemo options.

Geographical Location

The cost of veterinary care, including chemotherapy, can differ from one region to another. Urban areas and regions with a higher cost of living generally have higher veterinary fees. However, people in more rural areas may have to travel to find a vet that does chemotherapy.

Additional Care

Some dogs may need supportive care like hospitalization, medications to manage side effects, or nutritional support, which can increase overall costs.

Insurance Coverage

Pet insurance can help mitigate the financial burden of chemotherapy for dog owners. Depending on the policy, it may cover a portion of the treatment costs. However, you have to have insurance in place before diagnosis to receive these benefits.

Follow-Up and Monitoring

After the initial course of chemotherapy, follow-up visits and monitoring may be necessary, adding to the expense.

A dog owner must have open discussions with their veterinarian about anticipated chemotherapy costs, alternative treatment options, and other expenses. Pet owners should always explore financial assistance or pet insurance options to help manage the cost of canine cancer treatment.

Cost Breakdown

Initial Consultation and Diagnostic Tests

The first step is typically a consultation with a veterinary oncologist to assess the dog’s condition. This visit may cost around $150 to $300. Diagnostic tests such as biopsies, imaging, and blood work can confirm the type and stage of cancer, costing from $500 to $1500 or more.

Chemotherapy Drugs

The cost of chemotherapy can vary based on the drugs used, the dosage required, and the treatment protocol. Common dog chemotherapy drugs include doxorubicin, lomustine, vincristine, and prednisone. The price of these drugs can range from $20 to $200 per dose, and a full course of treatment may require multiple doses over several months.

Frequency and Number of Treatment Sessions

Chemotherapy is often administered in 4 to 12 treatments, depending on the type and stage of cancer. Treatment sessions can be weekly, biweekly, or monthly. Each session may cost between $200 to $600 or more, depending on the drugs used and the veterinary clinic’s fees. However, there is a great deal of variability between treatments, which can impact exact costs.

Monitoring Tests

Dogs require regular tests to assess their response to chemotherapy and detect potential side effects. These tests can include bloodwork, imaging, and other diagnostics. Monitoring blood work can range from $100 to $300, but specialized tests and imaging can cost more.

Supportive Care and Medications

Chemotherapy can produce nausea, vomiting, and decreased white blood cell counts. Supportive care may include medications to manage these side effects and ensure the dog’s well-being. The cost of supportive drugs can vary but may add several hundred dollars to the total expense.


Dogs may sometimes require hospitalization, particularly after certain chemotherapy treatments. Hospitalization can range from $500 to $1,500 per day.

Does Pet Insurance Cover Chemotherapy for Dogs?

Pet insurance often covers dog chemotherapy. However, the extent of coverage can vary depending on the insurance plan and provider. Most pet insurance policies cover a portion of the costs associated with chemotherapy. Review the policy details to understand what is included and excluded.

Inclusions and Exclusions

Typical inclusions in pet insurance may include reimbursement for chemotherapy drugs, diagnostic tests, consultations with veterinary oncologists, and a portion of the cost of monitoring tests.

Some exclusions include pre-existing conditions, certain breeds, types of cancer, and waiting periods that apply before coverage begins. To ensure chemotherapy coverage, pet owners should thoroughly read and understand the policy, including its limits, deductibles, and copayments.

While pet insurance can help offset the cost of chemotherapy for dogs, always anticipate some out-of-pocket expenses. Pet insurance policies often have deductibles before coverage begins and annual coverage limits or reimbursement percentages that may not cover the full cost of treatment. Some policies may have waiting periods before covering specific conditions. Discuss these details with the insurance provider and choose a policy that aligns with the expected cost of chemotherapy for your dog’s specific condition.

Alternative Treatments

Several alternative treatment modalities are available for dogs facing cancer. Surgical options can remove localized tumors or masses, and the extent of the surgery depends on the type and stage of cancer.

Removing the cancerous tissue may offer a cure. Radiation therapy uses high-energy X-rays to target and shrink tumors while seeking to spare surrounding healthy tissue. It can be effective for localized cancers or as an adjunct to surgery or chemotherapy.

Holistic and complementary treatments, such as acupuncture, herbal supplements, and dietary changes, can support conventional therapies to improve a dog’s well-being and manage cancer-related symptoms. Immunotherapy and targeted treatments, a rapidly evolving field in veterinary oncology, harness the immune system or specific molecular pathways to target cancer cells more precisely.

These treatments hold promise for both palliative and curative approaches. Veterinarians work closely with pet owners to determine the most appropriate combination of treatments based on the dog’s specific diagnosis and overall health.

Post-Chemotherapy Recovery and Care

Recovery and care require careful attention to ensure your dog’s comfort and well-being. Following a chemotherapy session, expect your dog to experience side effects such as fatigue, nausea, and changes in appetite. Rest is crucial, and dogs may need a quiet, comfortable place to recuperate. Monitor them for adverse reactions or worsening symptoms, such as vomiting, diarrhea, lethargy, or inappetence, and inform the veterinarian if any issues arise. The veterinary team will guide pet owners on managing side effects and may prescribe medications to alleviate nausea or support the immune system.

Dietary recommendations play a pivotal role in post-chemotherapy care. Maintaining good nutrition is essential to help the dog’s body recover and tolerate subsequent treatments. The veterinarian may suggest a special diet or supplements to address specific needs, such as a high-calorie diet to combat weight loss or a gentle diet for dogs with gastrointestinal issues. Supportive care continues throughout the treatment process, with regular monitoring to assess the dog’s response and adjust the treatment plan as needed.

Long-term prognosis depends on the type and stage of cancer and the dog’s response to treatment. Some dogs may achieve remission and enjoy a good quality of life for an extended time, while others may require ongoing palliative care. Regular follow-up appointments and monitoring are essential to track the dog’s progress and detect any recurrence or new health concerns.



Finding the balance between treatment effectiveness, quality of life, and cost is paramount in canine chemotherapy. Pet owners should seek guidance from veterinary oncologists to make informed decisions about their dog’s cancer treatment. Each case is unique, and the treatment must match the dog’s needs and owner's limitations.

The primary focus as caregivers is to weigh the potential benefits of chemotherapy against its side effects and financial implications. Regular consultations with veterinarians and veterinary oncologists, honest communication, and monitoring of the dog’s health are crucial to navigating this challenging journey. Informed decisions, personalized treatment plans, and unwavering dedication can give our beloved pets the best chance for a fulfilling life, even in the face of cancer.

About The Author

Andy Chang

Andy Chang

Founder of InsuranceRanked

Andy Chang is the founder of InsuranceRanked, a review site dedicated to helping consumers find the best companies in financial services. Andy is passionate about financial education and wellness, and helping others reach financial freedom. He consistently writes about topics ranging from credit to banking and lending.

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